PUBLICATION
1. Matsumoto M, Tsuneyama K, Morimoto J, et al. Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanism.
Int. Immunol. doi: 10.1093/intimm/dxz066, 2019.
2. Matsumoto M, Nishijima H, Morimoto J, et al. AIRE - The autoimmune regulator.
eLS doi: 10.1002/9780470015902.a0027281, 2019.
3. Morimoto J, Nishikawa Y, Kakimoto T, et al. Aire controls in trans the production of medullary thymic epithelial cells expressing Ly-6C/Ly-6G.
J. Immunol. 201:3244-3257, 2018.
4. Nishijima H, Kajimoto T, Matsuoka Y, et al. Paradoxical development of polymyositis-like autoimmunity through augmented expression of autoimmune regulator (AIRE).
J. Autoimmun. 86: 75-92, 2018.
5. Mouri Y, Ueda Y, Yamano T, et al. Mode of tolerance induction and requirement for Aire are governed by the cell types that express self-antigen and those that present antigen.
J. Immunol. 199: 3959-3971, 2017.
6. Matsumoto M. Switching on the Aire conditioner.
Eur. J. Immunol. 45: 3237-3240, 2015.
7. Kawano H, Nishijima H, Morimoto J, et al. Aire expression is inherent to most medullary thymic epithelial cells during their differentiation program.
J. Immunol. 195: 5149-5158, 2015.
8. Nishijima H, Kitano S, Miyachi H, et al. Ectopic Aire expression in the thymic cortex reveals inherent properties of Aire as a tolerogenic factor within the medulla.
J. Immunol. 195: 4641-4649, 2015.
9. Mouri Y, Nishijima H, Kawano H, et al. NIK in thymic stroma establishes central tolerance by orchestrating cross-talk with not only thymocytes but also dendritic cells.
J. Immunol. 193: 4356-4367, 2014.
10. Nishikawa Y, Nishijima H, Matsumoto M, et al. Temporal lineage tracing of Aire-expressing cells reveals a requirement for Aire in their maturation program.
J. Immunol. 192: 2585-2592, 2014.
11. Matsumoto M, Nishikawa Y, Nishijima H, et al. Which model better fits the role of Aire in the establishment of self-tolerance: the transcription model or the maturation model (Review)?
Front. Immunol. 4: Article number 210, 2013.
12. Mouri Y, Yano M, Shinzawa M, et al. Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma.
J. Immunol. 186: 5047-5057, 2011.
13. Matsumoto M. Contrasting models for the roles of Aire in the differentiation program of epithelial cells in the thymic medulla (Review).
Eur. J. Immunol. 41: 12-17, 2011.
14. Nishikawa Y, Hirota F, Yano M, et al. Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation.
J. Exp. Med. 207: 963-971, 2010.
15. Matsumoto M. The role of autoimmune regulator (Aire) in the development of the immune system (Review).
Microbes Infect. 11: 928-934, 2009.
16. Yano M, Kuroda N, Han H, et al. Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance.
J. Exp. Med. 205: 2827-2838, 2008.
17. Matsumoto M, Zhou Y, Matsuo S, et al. Targeted deletion of the murine corneodesmosin gene delineates its essential role in skin and hair physiology.
Proc. Natl. Acad. Sci. USA 105: 6720-6724, 2008.
18. Matsumoto M. Transcriptional regulation in thymic epithelial cells for the establishment of self tolerance (Review).
Arch. Immunol. Ther. Exp. 55: 27-34, 2007.
19. Niki S, Oshikawa K, Mouri Y, et al. Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice.
J. Clin. Invest. 116: 1292-1301, 2006.
20. Kinoshita D, Hirota F, Kaisho T, et al. Essential role of IκB kinase α in thymic organogenesis required for the establishment of self-tolerance.
J. Immunol. 176: 3995-4002, 2006.
21. Kuroda N, Mitani T, Takeda N, et al. Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice.
J. Immunol. 174: 1862-1870, 2005.
22. Akiyoshi H, Hatakeyama S, Pitkanen J, et al. Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner.
J. Biol. Chem. 279: 33984-33991, 2004.
23. Kajiura F, Sun S, Nomura T, et al. NF-κB-inducing kinase establishes self-tolerance in a thymic stroma dependent manner.
J. Immunol. 172:2067-2075, 2004.
24. Uchida D, Hatakeyama S, Matsushima A, et al. AIRE functions as an E3 ubiquitin ligase.
J. Exp. Med. 199:167-172, 2004.
25. Matsumoto M, Yamada T, Yoshinaga SK, et al. Essential role of NF-κB-inducing kinase in T cell activation through the TCR/CD3 pathway.
J. Immunol. 169:1151-1158, 2002.
26. Matsushima A, Kaisho T, Rennert PD, et al. Essential role of NF-κB-inducing kinase and IκB-kinase α in NF-κB activation through lymphotoxin-β receptor, but not though TNF receptor-I.
J. Exp. Med. 193:631-636, 2001.
27. Yamada T, Mitani T, Yorita K, et al. Abnormal immune function of homopoietic cells from alymphoplasia (aly) mice, natural strain with mutant NF-κB-inducing kinase.
J. Immunol. 165:804-812, 2000.
28. Matsumoto M, Iwamasa K, Rennert PD, et al. Involvement of distinct cellular compartments in the abnormal lymphoid organogenesis in lymphotoxin-α-deficient mice and alymphoplasia (aly) mice defined by the chimeric analysis.
J. Immunol. 163:1584-1591, 1999.
29. Matsumoto M, Fu Y-X, Molina H, et al. Distinct roles of lymphotoxin-α and the type I TNF receptor in the establishment of follicular dendritic cells from non-bone marrow-derived cells.
J. Exp. Med. 186: 1997-2004, 1997.
30. Matsumoto M, Fukuda W, Circolo A, et al. Abrogation of the alternative complement pathway by targeted deletion of murine factor B.
Proc. Natl. Acad. Sci. USA 94: 8720-8725, 1997.
31. Matsumoto M, Fu Y-X, Molina H, et al. Lymphotoxin-α deficient and TNF receptor-I-deficient mice define developmental and functional characteristics of germinal centers.
Immunol. Rev. 156: 137-144, 1997.
32. Matsumoto M, Lo SF, Carruthers CJL, et al. Affinity maturation without germinal centres in lymphotoxin-α-deficient mice.
33. Matsumoto M, Mariathasan S, Nahm MH, et al. Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers.